Alzheimer's Disease
Examine neural networks in Alzheimer's disease and how they change over time
|
Maestro Volt |
The Maestro Volt™ makes quality MEA data accessible to any lab. The introductory MEA system is our most budget-friendly offering, designed for labs with lower throughput needs.
Compatible with our 6-well CytoView MEA™ plates and the Neural or Cardiac module, Maestro Volt allows for noninvasive electrophysiological evaluation of your cells in an easy-to-use in vitro assay. Capture the dynamic electrical activity of excitable cells (e.g. neurons and cardiomyocytes) and see how Maestro Volt can supercharge your research.
Compatible with our 6-well CytoView MEA™ plates and the Neural or Cardiac module, Maestro Volt allows for noninvasive electrophysiological evaluation of your cells in an easy-to-use in vitro assay. Capture the dynamic electrical activity of excitable cells (e.g. neurons and cardiomyocytes) and see how Maestro Volt can supercharge your research.
ÁRAJÁNLATOT, INFORMÁCIÓT KÉREK!
>> Save on cost
The same quality MEA data at a budget-friendly price.
>> Create detailed functional profiles
Dynamic spatial and temporal functional data evaluates how cells fire and interact in culture.
>> Monitor cells noninvasively
Noninvasive electrodes track activity over time for in-depth developmental studies and maximum experimental flexibility.
>> Precisely control the cells’ environment
The smart environmental chamber finely controls temperature and CO₂ while rejecting electrical noise and mechanical vibrations.
>> See your cells
Maestro’s patented CytoView transparent circuit technology allows easy cell visualization and assay multiplexing.
>> Control cellular activity
Electrical stimulation lets you recreate specific patterns of cellular activity.
>> Perform complex experiments with simple assay techniques
Requires only basic culture techniques with no labels, dyes, or complicated steps.
Multiplex your assay: Maestro + Omni
>> Platform cross-compatibility lets you view live-cell imaging alongside real-time, functional data to enhance your analysis
>> Monitor electrode coverage and cell morphology to ensure consistent, quality results
>> Experience no-hassle tracking — the Axion Portal automatically links data via barcode
Maestro Volt overview
Electrical activity can give important context to your research. Detailed functional characterization is critical for understanding disease mechanisms, but many researchers avoid it because the techniques can be laborious. Electrophysiology doesn’t have to be difficult.
The Maestro MEA platform makes it easy to perform complex electrophysiological experiments and gain deep insights into the function of cells. Since launching our first multiwell plate-based Maestro MEA system more than a decade ago, it has become an indispensable tool in academic, biotech, and pharma labs around the world.
Customize your Maestro Volt system for your assay needs:
Műszaki specifikációk
Applikációk
Related Applications
Amyotrophic Lateral Sclerosis (ALS)
Study molecular mechanisms of disease and neural network activity using in vitro ALS models
Autism
Explore neural network activity in autism spectrum disorder
Cardiac Classification
Predict the cardiomyocyte subtype using the action potential waveform in the LEAP assay
Cardiac Development
Track cardiac differentiation and maturation over weeks and determine when cardiomyocytes start to beat and form a syncytium
Cardiomyocyte Pacing
Control cardiomyocyte beat rate with optical or electrical stimulation to increase the physiological relevance of the assay
Cardiotoxicity and Safety
Evaluate the proarrhythmic risk of compounds in acute and chronic exposure experiments in CiPA-style studies
Epilepsy
A neurological disorder characterized by seizures from abnormal electrical activity in the brain
Glioma
A form of brain cancer that originates from glial cells.
Inotropy
Characterize compound-induced effects on cardiomyocyte inotropy and excitation-contraction coupling
Neural Characterization and Development
Monitor neural development and quantify network dynamics to identify unique properties of your culture
Neural Co-culture and Glial Interaction
A wide variety of neurons and other cells exist and interact together and the composition of a neural culture can alter development and disease progression
Neural Optical and Electrical Stimulation
Evoke neural activity with optical or electrical stimulation
Neural Organoids
Measure neural activity from live neural organoids and characterize advanced network behavior
Neuromuscular Junction
Record evoked skeletal myotube activity in functional iPSC-derived neuromuscular junctions
Neurotoxicology and Safety
Characterize the neuroactive properties of compounds in acute and chronic exposure experiments
Pain
Measure modulations of DRG neuron activity in response to chemical or temperature stimuli
Parkinson's Disease
Explore neural network behavior in Parkinson's disease models.
Tartozékok, kiszerelések
The Maestro Volt platform is available with one of two software modules: Neural or Cardiac. Select the software module to match your assay needs:
Neural – Measure the key parameters of neural network function, including activity (are the neurons functional?), synchrony (are the synapses functional?), and oscillation (is the network functional?).
Cardiac – Record the four key measures of functional cardiac performance, label free and in real time in every well of the multiwell plate: action potential (a.k.a. LEAP assay); field potential; propagation; and contractility.
Peripherals
The Maestro Volt is compatible with:
MEA Creator Kit – Connect user-made MEAs to Maestro MEA systems. Test your electrode designs, layouts, and integrate additional components with an easy-to-use adapter plate.
Consumables
The Maestro Volt is compatible with:
CytoView MEA™ – The premium Maestro multiwell MEA plate with a transparent well bottom for cell visualization and assay multiplexing. The 6-well plate formats are compatible with the Maestro Volt.
Cross-compatible Platforms
The Maestro Volt system has cross-compatibility with:
Omni™ – See whole-plate images of your cultures next to real-time activity measurements. Confirm electrode coverage and culture health with just a few clicks from AxIS Navigator™. Compatible with Omni and Omni Pro 12™ systems.
Videók, ismertetők
Forgalmazott termékeink gyártói - keressen gyártó szerint a logóra kattintva
